Lublin FD, et al. Neurology 2014;83:278–286.
Kappos L, et al. Mult Scler 2018;24:963–973.
Kappos L, et al. JAMA Neurol. doi:10.1001/jamaneurol.2020.1568. Published online June 8, 2020.

Lassmann H, et al. Nature Rev Neurol 2012;8:647–656.

Kurtzke J. Neurology 1983;33:1444–1452.
Weinshenker BG et al. Brain. 1989;112:133-146.
Confavreux C et al. N Engl J Med. 2000;343:1430-1438.
Compston A. McAlpine’s Multiple Sclerosis. 3rd ed. London: Churchill Livingstone.
Ebers et al. J Neurol 2006; 253 [S6]: VI/3–VI/8.

Smeets et al. Reliable measurements of brain atrophy in individual patients with multiple sclerosis. Brain Behav. 2016 Jul 19;6(9):e00518. eCollection 2016.
Absinta M et al. Neurology 2015;85:18–28.
Filippi M et al. Arch Neurol 68, 1514 – 1520, 2011.
De Stefano N, et al. Neurology 2010;74(23):1868–76.
Frischer JM, et al. Brain 2009;132(pt 5):1175–89.

Oxford GK ,et al. Am J Occup Ther 2003;570-573.
Feys P, et al. Mult Scler 2017; 23:711-720.
Giovannoni G et al, presented at Ectrims 2016 ( poster 746).
Schwid SR, et al. Neurology 2002;58(8):1294–6.
Yozbatiran N, et al. J Neurol Sci 2006;246(1–2):117–22.

Disanto G et al, ANN NEUROL 2017;81:857–870.
Harris VK, Sadiq SA. Mol Diagn Ther 2014;18(6):605–17.
Petzold A. J Neurol Sci 2005;233(1–2):183–98.

Parmenter BA et al. Mult Scler. 2007;13:52-57.
Smith A. Symbol Digits Modalities Test: Manual. Los Angeles, CA: Western Psychological Services; 1982.

National MS Society. http://www.nationalmssociety.org/For-Professionals/Researchers/Resources-for-Researchers/Clinical-Study-Measures/Timed-25-Foot-Walk-(T25-FW). Accessed August 2, 2016.
Hobart J, et al. Neurology 2013 ;80(16):1509–17.
Bosma LV, et al. Mult Scler 2012;18(3):345–50.